Prolonged Preservation Of The Heart Prior To Transplantation Essays

Prolonged Preservation of the Heart Prior to Transplantation Biochemistry Prolonged Preservation of the Heart Prior to Transplantation Picture this. A man is involved in a severe car crash in Florida which has left him brain-dead with no hope for any kind of recovery. The majority of his vital organs are still functional and the man has designated that his organs be donated to a needy person upon his untimely death. Meanwhile, upon checking with the donor registry board, it is discovered that the best match for receiving the heart of the Florida man is a male in Oregon who is in desperate need of a heart transplant. Without the transplant, the man will most certainly die within 48 hours. The second man's tissues match up perfectly with the brain-dead man's in Florida. This seems like an excellent opportunity for a heart transplant. However, a transplant is currently not a viable option for the Oregon man since he is separated by such a vast geographic distance from the organ. Scientists and doctors are currently only able to keep a donor heart viable for four hours before the tissues become irreversibly damaged. Because of this preservation restriction, the donor heart is ultimately given to someone whose tissues do not match up as well, so there is a greatly increased chance for rejection of the organ by the recipient. As far as the man in Oregon goes, he will probably not receive a donor heart before his own expires. Currently, when a heart is being prepared for transplantation, it is simply submerged in an isotonic saline ice bath in an attempt to stop all metabolic activity of that heart. This cold submersion technique is adequate for only four hours. However, if the heart is perfused with the proper media, it can remain viable for up to 24 hours. The technique of perfusion is based on intrinsically simple principles. What occurs is a physician carefully excises the heart from the donor. He then accurately trims the vessels of the heart so they can be easily attached to the perfusion apparatus. After trimming, a cannula is inserted into the superior vena cava. Through this cannula, the preservation media can be pumped in. What if this scenario were different? What if doctors were able to preserve the donor heart and keep it viable outside the body for up to 24 hours instead of only four hours? If this were possible, the heart in Florida could have been transported across the country to Oregon where the perfect recipient waited. The biochemical composition of the preservation media for hearts during the transplant delay is drastically important for prolonging the viability of the organ. If a media can be developed that could preserve the heart for longer periods of time, many lives could be saved as a result. Another benefit of this increase in time is that it would allow doctors the time to better prepare themselves for the lengthy operation. The accidents that render people brain-dead often occur at night or in the early morning. Presently, as soon as a donor organ becomes available, doctors must immediately go to work at transplanting it. This extremely intricate and intense operation takes a long time to complete. If the transplanting doctor is exhausted from working a long day, the increase in duration would allow him enough time to get some much needed rest so he can perform the operation under the best possible circumstances. Experiments have been conducted that studied the effects of preserving excised hearts by adding several compounds to the media in which the organ is being stored. The most successful of these compounds are pyruvate and a pyruvate containing compound known as perfluoroperhydrophenanthrene-egg yolk phospholipid (APE-LM). It was determined that adding pyruvate to the media improved postpreservation cardiac function while adding glucose had little or no effect. To test the function of these two intermediates, rabbit hearts were excised and preserved for an average of 24.5 1 0.2 hours on a preservation apparatus before they were transplanted back into a recipient rabbit. While attached to the preservation apparatus, samples of the media output of the heart were taken every 2 hours and were assayed for their content. If the compound

Affirmative Action Professor Ramos Blog

Affirmative Action Introduction Society is built off a hierarchy, whether that is through economic status or social status, we all have a place in it. This poses a problem and begs the question if there is fairness within our social network. In this report I will introduce the concept of affirmative action, who it has affected society within the workforce and education systems, explain the positives and negatives of affirmative action, and finally analyze what would happen if affirmative action did not exist. What is Affirmative Action? Affirmative action is a policy that intended to integrate the minority group in order to â€Å"[revert] discrimination† (Holzer and Neumark 13). This, in a way, diffused the lines of social boundaries among people of ethnic backgrounds to maintain an equal playing field. Affirmative action was an attempt to retaliate against racial and ethnic discrimination, especially discrimination against African Americans. It was then first used under the executive order of former President John F. Kennedy in 1961 for the purpose of ensuring that the people are treated equally without regard of their ethnic background (AAED). Former President John F. Kennedy intended affirmative action not only to target individuals of color, but regardless of their gender, social status, etc. At first, this policy initially â€Å"focused on improving opportunities for african americans in employment and education† in an attempt to bring equality among the white and blacks, becoming the byproduct of the 1960s Civil Rights Movement (NCSL). The sequence   of events that took place within the oppression of african americans and other minorities that would later come became the recipe of creating the policy of affirmative action. Who is Affected by it? In today’s society, affirmative action technically affect everyone in someway. But in terms of being affected in a beneficial manner, it mainly targets the minority group like african americans, latinos, asians. But affirmative action does not only help those of color, women of different ethnicity are also affected. Statistics reveal that â€Å"6 million women overall had advances at their job that would not have been possible without affirmative action† (Massie). This is significant as it implies that without the policy of affirmative action, there was a possibility that about 6 million would be unemployed or would not have advance in their field of work. Pros and Cons of Affirmative Action Throughout the decades, affirmative action has thrived and benefitted many individuals into a more fair society. Starting with the positives of affirmative action, the most obvious benefit of this policy is that it aids those that are disadvantaged and creates an opportunity to advance in school and work environments (Ayres). This policy opens the possibility for many social environments not to be predominantly white, thus creating and promoting a diverse environment. Another positive effect of affirmative action is that it would facilitate and compensate for centuries of oppression against minorities (Ayres). From the enslavement of african americans and native americans or the japanese internment camps used against the japanese-americans, many would see affirmative action as a way to make up for history’s worth of discrimination and segregation. Although affirmative action provides opportunities and aid in alleviating for the less fortunate, this policy is also not advocated by everyone. There are many that believe that affirmative action also brings up problems into society. Protestors of affirmative action believe it is doing the opposite of what it was intended to â€Å"[serving] as a reverse discrimination† (Ayres). Many are convinced that affirmative action is actually hurting those who are qualified for the task by not being picked over a minority or other ethnic group. Another negative effect of affirmative action is the possibility of reinforcing stereotypes (Ayres). This could be possible among many school or workplace environment as individuals may see minorities do not fit the respective environment. Another article addresses how over 90,000 employees filed employment discrimination complaints towards the Equal Employment Opportunity Commission in 2009 (Gaile). This implies that although minorities were giv en the opportunity to be provided work, it does not guarantee the dissipation of racial and ethnic differences. As a result it would, in turn, create and hinder working and schooling institutions. One academic paper accentuates affirmative action would force employers to lower working standards, with the possible consequence that continuous poor performance by the preferred workers will only result in reinforce negative prejudices (Coate and Loury 1221). It is suggesting that by choosing applicant through the process of affirmative action, companies and businesses would be cornered to change their standards. This would indirectly result in a less selective process and ultimately hurt the labor market. A World With no Affirmative Action The policy of affirmative action has certainly affected and shifted society’s social boundaries in ways that are both beneficial and hindering. But it is worth to dwell on the idea of a society that do not use affirmative action. In one study, â€Å"New York Times† presented statistics illustrating the state of California approving the statewide ban of affirmative action and the decline of enrollment rates among hispanics and blacks, with less than five percent of hispanics and less than one percent (â€Å"How Minorities Have Fared†). With the absence of affirmative action it is clear that the enrollment of minorities will decline, leaving the white population overrepresented. Furthermore, another article it pointed out states that were â€Å"post-affirmative action† showed a decline of minority applicants by about twenty-three percent. The repeal of affirmative action resulted in the minority applicants to be neglected and therefore affecting the balance of an already underrepresented social group. Conclusion Affirmative action opens the door not to dissipate inequality but more to promote fairness. Although the main function of affirmative action is to blur the lines of social barriers, it does not certainly mean equality and diversity cannot be side-effects of affirmative action. Affirmative action also functions in a way that gives voice to the underrepresented. But affirmative action alone cannot solve the many social differences that occur. Historically, The Brown v. Board of Education decision, that outlawed school segregation, in 1954 and the Civil Rights Act of 1964 along with affirmative action policies were not enough to integrate African Americans and other minorities into the mainstream social infrastructure. Policies alike even today are not sufficient in maintaining equality and equity, and so, affirmative action paves the way of opening a broader spectrum of more acceptance within social differences. Ayres, Crystal. â€Å"20 Principal Pros and Cons of Affirmative Action.† Green Garage, 19 Aug. 2015, greengarageblog.org/20-principal-pros-and-cons-of-affirmative-action. Bautsch, Brenda, and Suzanne Hultin. Affirmative Action | Overview, ncsl.org/research/education/affirmative-action-overview.aspx. Coate, Stephen; Loury, Glenn C. â€Å"Will Affirmative-Action Policies Eliminate Negative Stereotypes?† The American Review, Vol. 83, No. 5. (Dec 1993), pp. 1220-1240. Gaille, Brandon. â€Å"25 Important Statistics on Affirmative Action in the Workplace.† BrandonGaille.com, 23 May 2017, brandongaille.com/24-important-statistics-on-affirmative-action-in-the-workplace/. â€Å"History of Affirmative Action | American Association for Access Equity and Diversity.† AAAED, aaaed.org/aaaed/history_of_affirmative_action.asp. Holzer, Harry; Neumark, David. â€Å"ASSESSING AFFIRMATIVE ACTION.† NATIONAL BUREAU OF ECONOMIC RESEARCH. August 1999, NBER Working Paper No. 7323 â€Å"How Minorities Have Fared in States With Affirmative Action Bans.† The New York Times, The New York Times, 24 June 2013, archive.nytimes.com/www.nytimes.com/interactive/2013/06/24/us/affirmative-action-bans.html. Kiesel, Laura. â€Å"What Happens When Theres No Affirmative Action.† TheStreet, 11 Feb. 2014, thestreet.com/story/12321563/1/what-happens-when-theres-no-affirmative-action.html.Massie, Victoria M. â€Å"White Women Benefit Most from Affirmative Action and Are among Its Fiercest Opponents.† Vox, Vox, 23 June 2016, vox.com/2016/5/25/11682950/fisher-supreme-court-white-women-affirmative-action.

Load a DLL From a Resource Directly From Memory

Load a DLL From a Resource Directly From Memory Article idea by Mark E. Moss The article how to store a DLL inside a Delphi program exe file as a resource explains how to ship a DLL with your Delphi application executable file as a resource. Dynamic link libraries contain sharable code or resources, they provide the ability for multiple applications to share a single copy of a routine (or resource) they have in common. Using resource (.RES) files, you can embed (and use) sound files, video clips, animations and more generally any kind of binary files in a Delphi executable. Loading DLLs From Memory if a DLL stored in a RES can be used without first saving it on the file system (hard disk) According to the article Loading a DLL from memory by Joachim Bauch, this is possible. Heres how Joachim looks at the issue: The default windows API functions to load external libraries into a program (LoadLibrary, LoadLibraryEx) only work with files on the filesystem. Its therefore impossible to load a DLL from memory. But sometimes, you need exactly this functionality (e.g. you dont want to distribute a lot of files or want to make disassembling harder). Common workarounds for this problems are to write the DLL into a temporary file first and import it from there. When the program terminates, the temporary file gets deleted. The code in the mentioned article is C, the next step was to convert it to Delphi. Luckily, this has already been done by Martin Offenwanger (the author of DSPlayer). Memory Module by Martin Offenwanger is an extended Delphi (and also Lazarus) compatible version of Joachim Bauchs C Memory Module 0.0.1. The zip package includes the complete Delphi source code of the MemoyModule (BTMemoryModule.pas). Furthermore theres a Delphi and sample included to demonstrate how to use it. Loading DLLs From Resources From Memory If a demo DLL is stored as a resource using the RC file: DemoDLL RCDATA DemoDLL.dll varms : TMemoryStream;rs : TResourceStream;beginif 0 FindResource(hInstance, DemoDLL, RT_RCDATA) thenbeginrs : TResourceStream.Create(hInstance, DemoDLL, RT_RCDATA);ms : TMemoryStream.Create;tryms.LoadFromStream(rs);ms.Position : 0;m_DllDataSize : ms.Size;mp_DllData : GetMemory(m_DllDataSize);ms.Read(mp_DllData^, m_DllDataSize);finallyms.Free;rs.Free;end;end;end; varbtMM: PBTMemoryModule;beginbtMM : BTMemoryLoadLibary(mp_DllData, m_DllDataSize);tryif btMM nil then Abort;m_TestCallstd : BTMemoryGetProcAddress(btMM, TestCallstd);if m_TestCallstd nil then Abort;m_TestCallstd(This is a Dll Memory call!);exceptShowmessage(An error occoured while loading the dll: BTMemoryGetLastError);end;if Assigned(btMM) then BTMemoryFreeLibrary(btMM);end; Have / Create a DLLStore the DLL in a RES fileHave BTMemoryModule implementation.Grab the DLL from the resource and load it directly into memory.Use BTMemoryModule methods to execute procedure from the DLL in memory. BTMemoryLoadLibary in Delphi 2009, 2010, ... The linked BTMemoryModule.pas does not work with Delphi 2009 (and I would assume Delphi 2010 also).I found a similar version of the BTMemoryModule.pas file a while ago, and made changes so it works with (at least) Delphi 2006, 2007 and 2009. My updated BTMemoryModule.pas, and a sample project, are at BTMemoryLoadLibary for Delphi 2009

Attend an Employment Tribunal and write a court report about your Essay - 1

Attend an Employment Tribunal and write a court report about your visit and what you witnessed - Essay Example The ground for his dismissal was not fair. Mr R Rembiszewski had been working for Atkins Ltd for a period of 16 years. He initially joined the company as a Railway architect, a position he held for four years, before he was promoted to the position of the deputy design officer. After working in this department for two years, his boss left, making this position vacant. After a thorough consideration by the Board of directors, he was found suitable to hold the position, and thus was promoted to become the design officer of the company. This was a clear indication that his hard work and efforts were recognized by the company. However, he was never promoted anymore during his tenure in the company, although many promotions had been made. His concern about this saw him protest against discrimination during promotions. This led to his dismissal without of reasonable notice (Painter & Holmes, 2011 p28). The Employment Tribunal had to consider these issues under a single case filed by Mr R R embiszewski, and determine the case appropriately. Lawyers represented each party to the case, where they argued the case for their clients. The facts regarding this case were first presented by Mr Rembiszewski’s lawyer. According to him, there were a series of promotions that occurred in the company during the 16 years that he had worked with the company, yet he had only been promoted twice. According to Mr Rembiszewski, an employee was eligible for promotion if he/she had worked with the company for a minimum of five years, as provided for by company’s policies. This meant that he ought to have been promoted at least three times. The facts also stated that he protested this discrimination, since most of his colleagues, who had worked with the company for a similar duration, had obtained their fair share of promotions. After protesting, the management of the company

Gas line explosion in Fresno Essay Example | Topics and Well Written Essays - 750 words

Gas line explosion in Fresno - Essay Example During the explosion, at least 11 people were injured. Most of the victims were inmates who were near the blast site. In this case, the inmates had been assigned cleaning and maintenance duties at the firing range (Marcum & Therolf, 2015). However, three other inmates were unhurt. Firefighters assigned to put out the explosion revealed that, the blaze blackened front loader and formed a crater at the site. The explosion however did not create property damage in the area. Although there were no indications that the PG&E Company had a hand in the fiery accident, the Fresno County Sheriffs are investigating the company’s natural-gas operations. Extensive scrutiny is conducted due to the company’s natural-gas operations that killed at least 8 people after the San Francisco blast in San Bruno suburb (Marcum & Therolf, 2015). On the other hand, the National Transportation Safety Board is blaming PG&E safety practices and Iax lapse by state regulators especially for this occurrence. The State regulators had earlier leveled the biggest-ever fine against utility in the state to cost at least $1.6 billion. This was against PG&E for its role in the Bruno blast (Marcum & Therolf, 2015). Catastrophic pipeline emergencies remain rare. However, with the increasing pipeline catastrophes across the United States, adequate preparation and responses remain important in minimizing life and property risks from pipeline emergencies. To plan effectively for pipeline catastrophes, it is important that emergency responders understand how best the emergency response works. Additionally, the authorities in charge must use resources and tools available in assisting with disaster preparedness and response. Excavators and pipeline organizations must always coordinate before digging. Communities must also consider implementing some of the recommended practices by the PIPA. Most of these recommendations address on people and property protection. They also

Thinking Styles and Decision Making Essay Example for Free

Thinking Styles and Decision Making Essay Levels of thinking differed from one person to another. Each thinking style is influenced by our mainstream society, how we think and develop perception on the material things happening in the surroundings. There are a lot of thinking styles that came into being since the time of old ancestors to the recent modern developers of our age. There are twenty six thinking styles that was developed but we will concentrate our discussion on the three sub-divided types namely the Sensory focus, People focus, and Task focus. Other thinking styles are used in psychological workshops and research such as analyst thinking style, realist thinking style, idealist, synthesist, pragmatist and spiritually-guided thinking style (An Introduction to Thinking Styles,).   In 1995, original concept for the thinking styles was formulated by Fiona Beddoes-Jones to enhance professional and personal development (Thinking Styles,).   Thinking styles can help in dealing with different types of problems in the workplace, academe, family and relationships. The Three Different Thinking Styles   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Before we proceed it is necessary to define the three levels of thinking styles. Sensory Focus examines things by receiving information through the senses and used the senses to perceive actual events. It is manifested in the visual, auditory, kinaesthetic and digital thinking. Watching, observing and looking pictures, diagrams, and visual imagery are the simple ways of expressing visual thinking while auditory requires the use of words and language, listening and conversing things. Kinaesthetic thinking is expressed through feelings, intuition, emotions, and physical movement and exercise as digital thinking entails the use of data, facts and statistics and the degree of data rationality. On the other hand, People Focus is how people perceived to relate with other people on their direct environment. It is focused on different levels of thinking such as internal and external thinking, self-referenced, altruistic, conforming, challenging, collaborative and competitive thinking. Internal thinking depends on own judgments and decisions and only consider self-knowledge as right and disregards feedback from other people. Some other people tend to dislike their own ideas and are not confident to explore many possible views and usually rely on other people or groups of people to give feedback on certain issues and problems. These people are external thinkers. Moreover, self referenced thinking is an approach of putting their own needs first and disregards the needs of others. In contrast, altruistic thinking involves responding to the needs of others and is willing to extend their help to other people. Conforming thinkers tends to keep away from confrontations and will certainly take a non-challenging methods, in contrast to challenging thinkers who definitely wanted to take confrontations, debates and experiments. Competitive thinkers would like to aspire for competitions and wants to gain victory from their own performance. Persons who wanted duties defined and detailed-oriented are Task Focus thinkers. They are conscious of the details especially in workplace where information is being transmitted through detailed facts and information. The Task Focus thinkers are strategic, creative, logical, options, procedural, towards, troubleshooting, proactive, reactive, simplicity, complexity, sameness, and different thinkers (Ltd., 2005). These thinking styles are distinct from each other but may sometimes closely connected together. Different patterns of these styles are being used as understanding and communicating with other people in surviving the daily response to work and life system. The amount of understanding different types of problems requires thinking styles that may influence critical thinking process. Such mentioned types of styles are good considerations in problem solving and decision making process. Sensory thinking style can help improve relationship with other people in the workplace, school, organizations, friends, and even families. Non-verbal communication somehow helps in understanding different personalities and the way you can approach them when facing a contradiction. Senses can transmit information and analyze things just by looking, observing, listening, feeling, intuitions, and physical movements. By looking at a critical situation using this kind of style, one can already define and identify the drawbacks. Most persons who don’t want confrontations tends to choose sensory focus in delivering and receiving information towards a given situation or crisis within a workplace. While others opted to choose interaction and personal touch to listen and confront problems this is somehow difficult in relating to contradictions with other people. However, it is very effective in most groups of people who are open-minded and problems can be solved instantaneously. Alternatively, task focus is a better way of coping up things since it is focused on goals and targets, detailed information, possibilities and alternatives in solving problems. These type of styles are distinct to each other and generally have an effect on critical thinking process and can possibly help the outcome of the decision making process. The positive upshot makes life more constructive by knowing which style you are most confident and at ease or difficult to cope up with in acknowledging, appreciating, expressing or solving things and difficulties. It brings people together and means more efficiency in duties, constancy in having good health, development of self-being, and gaining more friends and social groups. Reference An Introduction to Thinking Styles [Electronic Version]. Retrieved June 2, 2007 from http://www.earthtym.net/s-general.html. Ltd., T. C. F. C. (2005). Thnking Styles [Electronic Version]. Retrieved June 2, 2007 from http://www.consultingtools.com/media/thinkingstyles.pdf. Thinking Styles [Electronic Version]. Retrieved June 2, 2007 from http://www.cognitivefitness.co.uk/.

A GROSS FORM OF DELIGHTFUL SATIRE Essays -- essays papers

A GROSS FORM OF DELIGHTFUL SATIRE "The stoical scheme of supplying our wants by lopping off our desires, is like cutting off our feet when we want shoes." -Jonathan Swift "We have just enough religion to make us hate, but not enough to make us love on another." -Jonathan Swift Like all true satirists, Swift was predominantly a moralist, one who chastises the vices and follies of humankind in the name of virtue and common sense. Throughout his writing, Swift constantly raised the question of whether the achievements of civilization-its advancing technology, its institutions, its refinement of manners-cannot be seen as complex forms of barbarism. With this theme in mind, Swift wrote some of his best works: A Modest Proposal, Gulliver’s Travels, and A Tale of a Tub. Although he is mastery at prose, he is also known for his poetry. It can be said that the subjects within his writings could be taken from his religious belief in the non-perfection of man. Swift believed that human reason was necessary to divine guidance. According to Herbert Read, Swift was the first poet who dared to describe nature as it is with all its deformities, and to give exact expression to a turn of thought no matter the subject. And because his life was one long mutiny- mutiny against darkness of fate, the injustice of men, the indignity of our bodily functions-his work is one long scrutiny into dark depths. Therefore, he attacks the idealistic idea of feminine beauty by ironically drawing attention to the female body’s excretory functions. Unfortunately, Swift emphasizes women, despite his deep love and friendship for individual women, as a symbol of man’s bestiality. He victimizes women by his own secret over-idealization of her. This is seen in his poems, The Lady’s Dressing-Room, Strephon and Chloe, and A Beautiful Young Nymph Going to Bed. Swift becomes obsessed by the morbidly physical. The gap between spirit and flesh cannot bridge, for flesh has become uncleansable to him. With Swift being seen by Robert Ellis--quoted by Herbert Read-as having neurasthenia, anything that comes regularly and in routine is liable to become intolerable, it is easier to understand some of his writings. This idea gained him much ridicule from critics because thinkers of his day stressed the essential goodness and rationality of humans. Swift, certainly, shares this i... ...od which he was writing and the subjects that were generally written about. Because his descriptions are so detailed, and the imagery is so deep, Jonathan Swift proves himself as a writer to be studied and admired. Bibliography: WORKS CITED Brown, Laura. â€Å"Reading Race and Gender: Jonathan Swift.† Critical Essays on Jonathan Swift. Ed. Frank Palmeri. New York: G.K. Hall & Co, 1993. 122. Davis, Herbert. â€Å"Swift’s View of Poetry.† Poetry Criticism. Ed. Drew Kalasky. Vol. 9. Detroit: Gale Research Company, 1994. 259 Donoghue, Denis, Ed. Jonathan Swift. Australia: Penguin Books, 1971. 307. Huxley, Aldous. â€Å"Do What You Will.† London: Chatto & Windus, 1956. Johnson, Maurice. â€Å"The Sin of Wit: Jonathan Swift as a Poet.† Literature Criticism from 1400 to 1800. Ed. Dennis Poupard. Vol. 1. New Jersey: Gale Research Company, 1984. 502. Read, Herbert. â€Å"The Poems of Swift.† Literature Criticism from 1400 to 1800. Ed. Dennis Poupard. Vol. 1. New Jersey: Gale Research Company, 1984. 453. Watkins, W.B.C. â€Å"Absent Thee from Felicity.† Literature Criticism from 1400 to 1800. Ed. Dennis Poupard. Vol. 1. New Jersey: Gale Research Company, 1984. 461.